Metal Mediated Defunctionalization:

 

The removal of functional groups from organic molecules are immensely important in synthesis of natural products and in biological processes. Synthetically, the utility of functional groups is mainly due to their ability to act as directing groups as well as high reactivity and selectivity in a wide variety of transformations. In this context metal mediated defunctionalization has attracted attention of chemists for decades since such processes enable temporary use of the beneficial features of functional groups.

Representative Publications

Metal Mediated Deformylation Reactions: Synthetic and Biological Avenues.

Angew. Chem. Int. Ed. 2011, 50, 12140-12142

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